can use ethanol can be replaced at a very high rate ( ethanol available as natural curing grade) but if it is an oral product May not be very good for oral useFour-EO™ To mix with water Any natural solvent or natural origin can be used instead. Poloxamer 407
The manufacturer has not disclosed but it is a chemically processed agro ingredient.- Polyglyceryl-4 Caprate is of plant origin or natural group