Cosmetics Formulation Development

Inquire about the properties of substances in the group. penetration enhancer as follows 1. If comparing Laurocapram (Water Soluble penetration enhancer ) vs. 1,2-Hexanediol vs. PE-1 Aqua Want to know which one is effective for absorption/ นำพาสาร Active That dissolves in water into the skin is the best? 2. If the gel formula is very soft (with Pro Polymer is a mixture of only 0.2%-0.3. %) will be able to enter Reservoir-Tech 3% can it go down? yes? 3. Please confirm the substance in the list below that it is used with Laurocapram (Water Soluble penetration enhancer ) is that sure? (Please ask for permission not to specify as a formula that has been calculated % already because I still don't know if Active is interested or not) - WhiteCumin™ 2x ( สารสกัดขมิ้น ) --> Tetrahydro Curcumin is not soluble in water - Hi-EGCG™ (Green Tea Extract) --> EGCG is not soluble in water - Centella Asiatica Extract (Madecassoside 7.7%) --> Madecassoside does not dissolve in water - BaicaVital™ ( Scutellaria Baicalensis Extract --> Baicalin is not soluble in water - Salicylic Acid EZ™ (ชนิดละลายน้ำ) - Tomato Extract (Lycopene) - Grape Seed Extract ( Proanthocyanidins ) - French Pine Bark Extract 25 (Liquid) - Pep®-Coll ( Palmitoyl Tripeptide-5 ) - NAT-RIBOSE™ - Wrinkle-Lax™ Wrinkle removal - Cell-Energy™ (Adenosine) - Creatine 100 - Wrinkle-Fill™ ( L-Tyrosine ) - Panthenol (Pro Vitamin B5) - glycolic acid ( AHA ) - DMAE (SkinTight MD™) Liquid Thanks in advance

Hello

1. If you compare between Laurocapram (Water Soluble penetration enhancer ) vs. 1,2-Hexanediol vs. PE-1 Aqua Want to know which one is effective for absorption/ นำพาสาร Active Which is the best that dissolves in water into the skin?

There is no one that is the best. Each substance behaves differently. This will work well in different environments and variables. PE-1 Aqua is not suitable for use. นำพา The mixture is dissolved in water. Laurocapram and 1,2-Hexanediol No comparison test results. which type is better Only the test results of Laurocapram with more [that the test volume is more doesn't mean it's better 1,2-Hexanediol because when the test results of 1,2-Hexanediol Exit come more, so may be able to draw a better conclusion]

:arrow: 2. If the formula is very soft gel (with Pro Polymer is a mixture of 0.2%-0.3%), it will be able to enter Reservoir-Tech 3% can it go down?

If it's too liquid In this case, it is recommended to use Laurocapram which can be directly dissolved in water.

3. Please confirm the substance according to the list below that it is used with Laurocapram (Water Soluble penetration enhancer ) Is that right? (Please ask for permission not to specify a formula that has been calculated % already because I still don't know if Active is interested or not) - WhiteCumin™ 2x ( สารสกัดขมิ้น ) --> Tetrahydro Curcumin is insoluble in water - Hi-EGCG™ (Green Tea Extract) --> EGCG insoluble - Centella Asiatica Extract (Madecassoside 7.7%) --> Madecassoside not soluble - BaicaVital™ ( Scutellaria Baicalensis Extract --> Baicalin is not soluble in water - Salicylic Acid EZ™ (ชนิดละลายน้ำ) - Tomato Extract (Lycopene) - Grape Seed Extract ( Proanthocyanidins ) - French Pine Bark Extract 25 (Liquid) - Pep®-Coll ( Palmitoyl Tripeptide-5 ) - NAT-RIBOSE™ - Wrinkle-Lax™ Wrinkle removal - Cell-Energy™ (Adenosine) - Creatine 100 - Wrinkle-Fill™ ( L-Tyrosine ) - Panthenol (Pro Vitamin B5) - glycolic acid ( AHA ) - DMAE (SkinTight MD™) Liquid

This formula is not suitable for use. Laurocapram because some ingredients are dissolved in oil. In a formula like this it is recommended to use Phospholipid 2-3% help นำพา

Still confused by Staff's answer like you said. PE-1 Aqua is not suitable for use. นำพา Ingredients dissolve in water. But on the product detail page it clearly states " PE1-Aqua is สารนำพา ( penetration enhancer ) active ingredients into the skin It contains natural terpenes elements for use นำพา water-soluble ingredient. (water-soluble)" and then we ask that each substance in the list above applies to Laurocapram I don't want to include all Actives in the formula. same But it's alright Finally, disturbing the staff to confirm for us, just one is enough. [color=#0000FF] Salicylic Acid EZ™ (ชนิดละลายน้ำ) used with Laurocapram ?[/color ] Thanks in advance for your answer

Hello, the team is very sorry for the mistake. PE-1 Aqua is not suitable for use. นำพา oil-soluble ingredients.

Salicylic Acid EZ™ (ชนิดละลายน้ำ) Applies to Laurocapram

The team is not sure. Laurocapram will affect นำพา Salicylic Acid because Salicylic Acid itself is not directly soluble in oil or water, the team thinks Laurocapram will have the effect can make Salicylic Acid penetrates into the skin more, but more penetration into the skin of Salicylic Acid is not necessary. cause because Salicylic Acid works at the epidermis level. ผลัดเซลล์ผิว outer layer including ละลายสิวอุดตัน Deep absorption into the skin. It doesn't give any more benefit. If member's formula is used Salicylic Acid with other ingredients consider choosing penetration enhancer for other substances without any worries about Salicylic Acid