Cosmetics Formulation Development


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Ask about the best antioxidants.

Postby contact3 » Thu Nov 08, 2018 3:21 pm

I have to ask you to help answer. I will choose the Top 5 substances that are the best antioxidants. (And without irritation or clogging) Top 5 substances that help ลดการระคายเคือง the best (and does not clog) ------ due to want to dissolve วิตซี L-ascorbic acid and then use Ethoxydiglycol In the formula, only 2.6% has to choose another option to add. I would like to ask if Methyl Propanediol Isopentyldiol 1,2-Hexanediol Dimethyl Isosorbide (DMI) Glycerin 99.5% Which of these is dissolved? L-ascorbic acid can be used if heat helps. or get all Thank you very much
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Re: Message inquiry

Postby staff » Sat Nov 10, 2018 4:35 pm

Hello, about the subject anti-oxidation: no substance is the best Although only one measure of efficiency cause because real efficiency under different environment The various environmental conditions directly affect the effectiveness of the action, for example, in the past. antioxidant efficiency It is usually measured with Oxygen radical absorbance capacity (ORAC) and Total radical trapping Antioxidant potential (TRAP) but in reality These values It is measured in vitro, giving actual efficacy when used in cosmetics. there is a difference (And not related or called no-correlation) with the value measured in vitro at all. The composition of the formula has an important effect, but the effect is different. In the efficacy of each substance (in other words, assuming substance A is moderately effective in in vitro and at base X is good. Compared to substance B, it has excellent performance in in ลดการระคายเคือง , but when it is in base X, it is poor). ลดการระคายเคือง No substance alone is a perfect solution to irritation, simple substances that are properly applied can help ลดการระคายเคือง can be, for example, fatty alcohol and the problem of irritation has many characteristics and can be caused by many reasons. Therefore, there is no substance that solves the problem of irritation the best. Because each substance acts differently. If members develop a formula to solve irritation problems. Opting for expensive ingredients such as Licorice Extract (and possibly high doses) in the formulation that does not use bulk ingredients. moisturizer may not perform at all if users Irritated skin problems with a factor of dryness Therefore, development must consider various aspects. Usually, the team recommends Glycyrrhetinic Acid in a formula that wants to prevent irritation. If the formula has a chance to irritate the user's skin. (The team uses the word popular, wanting to convey that Glycyrrhetinic Acid is not the best) for solubility. L-ascorbic acid has already been answered in another thread. Disturbing members to refrain from asking again.
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