Adding EGF to Cosmetic Formula: Stability and Handling
Asked by: ruevilin
On: December 31, 2022
Product Type:
Cosmetics
Question
Can 5% water be replaced with 5% EGF in a cosmetic formula containing various peptides, extracts, and a gel maker, and what are the necessary considerations regarding pH, mixing, and storage to ensure the EGF remains stable and effective?
Answer
Based on the information for Epidermal Growth Factor (EGF, Recombinant), adding 5% is within the recommended usage rate (1-5%, with 3% typically recommended).
However, successfully incorporating EGF into your formula requires careful consideration:
- pH Stability: This specific EGF product is most stable at a pH of 3-5. You must ensure your final formulation's pH is within this range.
- Mixing Method: Add the EGF at the final step of your formulation process, ensuring the temperature is below 40°C (25°C recommended). Blend thoroughly until completely dissolved.
- Storage: The final product containing this EGF should be stored under refrigeration (4°C - 8°C).
Simply swapping water for EGF without adjusting the pH and following the specific mixing and storage instructions may lead to the EGF degrading and losing its effectiveness.
