Adding Peptides & Ferment Lysate to Physiogel Base - Dryness & Measurement

Using Physiogel Hypoallergenic as a base and adding active ingredients like Matrixyl 3000 and Argireline requires careful measurement to ensure the correct concentration. Experiencing dryness after adding these peptides suggests that the amount added might be too high for your skin, or the ingredients were not incorporated correctly without precise measurement.

Matrixyl 3000 (Pal-GHK, Pal-GQPR) is typically used at 3-5%, while Argireline (Acetyl Hexapeptide-8) is used at 3-10%. Adding too much of these active ingredients can potentially lead to skin dryness or irritation.

You asked if you can add Repair Activator (Bifida Ferment Lysate). This ingredient is generally compatible with peptides and is known for its skin barrier support properties. However, adding another active ingredient when you are already experiencing dryness is not advisable until the cause of the dryness is identified and resolved.

It is crucial to use a precise scale when adding active ingredients to a base to ensure you are using them within their recommended concentration ranges. Without accurate measurement, it is difficult to control the final formulation and predict its effect on your skin.

To address the dryness and safely proceed, it is recommended to:

• Provide the information requested by the staff regarding your previous use of Physiogel alone and how you estimated the amounts of Matrixyl 3000 and Argireline.
• Obtain a precise scale capable of measuring small quantities accurately.
• Once you have a scale, you can create a new, accurately measured batch of your mixture, starting with the lower recommended percentages of Matrixyl 3000 and Argireline (e.g., 3% for each) to see how your skin tolerates it.

After resolving the dryness issue and ensuring you can measure accurately, you can then consider adding Repair Activator (Bifida Ferment Lysate) at its recommended usage rate (typically 5-100% depending on the specific product concentration).

Adding multiple active ingredients can be beneficial, but it is essential to do so safely and effectively by controlling the concentrations through precise measurement.