Caffeine Substitution Calculation and Melatonin Forte Packaging Stability
คำถาม
I have two questions:
- How can I replace 5% Slim-Coffee (which contains 33% active caffeine) with pure Caffeine (100% active caffeine) in a hair loss reduction formula? What percentage of pure Caffeine should I use?
- Previously, I ordered Melatonin Forte™ in a syringe form, but now it is packaged in a bottle. Will the Melatonin Forte™ degrade before mixing or use because it is now in a bottle exposed to air, unlike the syringe which had less air exposure?
คำตอบ
Caffeine Substitution in Hair Loss Formula
To replace 5% Slim-Coffee (Coffee Extract) in a hair loss reduction formula with pure Caffeine (CF Powder), you need to consider the active caffeine content of each ingredient.
- Slim-Coffee (Coffee Extract) contains 33% active caffeine.
- Pure Caffeine (CF Powder) contains 100% active caffeine.
Five percent (5%) of Slim-Coffee provides 5% * 33% = 1.65% active caffeine.
Therefore, to achieve the same level of active caffeine using pure Caffeine, you should use 1.65% pure Caffeine (CF Powder).
Important Note: As mentioned by the staff, pure Caffeine (CF Powder) is difficult to dissolve in standard formulations and requires expertise to handle properly, unlike Coffee Extract which is water-soluble up to a certain level.
Melatonin Forte™ Packaging
Regarding the change in packaging for Melatonin Forte™ from syringes to bottles, the staff has explained that while bottles do allow for more air exposure compared to syringes, the company uses a gas flushing process when packaging the product in stock to minimize initial air contact.
They also noted that the syringe packaging had issues with the stopper degrading over time, leading to leakage. The change to bottle packaging was made despite the potential for gradual degradation after opening, as the syringe method presented different problems.
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CF Powder