Chloroxylenol 0.15% for Disinfection vs. Preservation in Liquid Soap
คำถาม
I am using powdered Chloroxylenol at a concentration of 0.15% in a liquid soap formula for disinfection. Is it necessary to add an additional preservative to the formula?
คำตอบ
Chloroxylenol (PCMX) at 0.15% in Liquid Soap
Using Chloroxylenol (PCMX) at a concentration of 0.15% in a liquid soap formula is primarily for its disinfectant properties, aiming to kill germs present during use.
However, disinfection and preservation are distinct functions:
- Disinfection: Killing microorganisms at a specific point in time.
- Preservation: Preventing the growth of microorganisms over the product's shelf life to maintain safety and stability.
According to the information available, the FDA allows Chloroxylenol to be used as a preservative in cosmetic formulas at a maximum rate not exceeding 0.5%. While 0.15% has disinfectant activity, it is below this recommended maximum for preservation.
Therefore, even though 0.15% Chloroxylenol provides disinfectant benefits, it is generally necessary to include a separate, broad-spectrum preservative system in your liquid soap formula to ensure long-term microbial stability and prevent contamination throughout its shelf life.
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