Combining Activated Resorcinol and AHA: Formulation Guidance

Hello,

Regarding the use of Activated Resorcinol with AHA, here is detailed guidance based on your questions:

1. Acidity of AHA: The primary concern when combining Activated Resorcinol with AHA is the pH level of the final product, rather than simply the percentage of AHA used. Activated Resorcinol is most stable and effective within a pH range of 4.5-5.5. While a formula containing 1% Lactic Acid and 1% Activated Resorcinol adjusted to pH 4.5 falls within this optimal range, the general recommendation is to avoid this combination. This is because the presence of AHA's acidity, even when the final pH is adjusted, may still impact the long-term quality and stability of Activated Resorcinol. For optimal stability and performance, it is generally advised not to use them together in the same formulation.

2. Alternative Exfoliants: If you require exfoliation in a formula containing Activated Resorcinol and wish to avoid AHA, consider incorporating enzyme exfoliants or Polyhydroxy Acids (PHAs). These ingredients typically offer milder exfoliation and can often function effectively at pH levels that are more compatible with the optimal range of Activated Resorcinol (4.5-5.5).

   • Bio-S Protease™ is a natural protease enzyme known for its gentle exfoliation properties and wide pH stability (4-12), making it highly suitable for use with Activated Resorcinol.
   • Malt-Exfo™ (Maltobionic acid), a type of PHA, is another option for gentle exfoliation. PHAs are generally less irritating than AHAs and may offer better compatibility, although specific pH testing within your formula is always recommended to ensure stability.
   • Salicylic Acid (BHA) is also acidic and might present similar compatibility challenges as AHAs.

3. Using ActiveProtec™ OX: ActiveProtec™ OX is an antioxidant blend designed to prevent oxidation and discoloration of sensitive ingredients like Activated Resorcinol, thereby enhancing overall formula stability. It is effective in acidic environments (resistant below pH 4). While ActiveProtec™ OX can help protect Activated Resorcinol from oxidation-related degradation, it may not fully mitigate the potential instability caused by the direct interaction of AHA's acidity with the Activated Resorcinol molecule itself. Therefore, while using ActiveProtec™ OX is beneficial for preventing discoloration and oxidation, it is still generally recommended to avoid combining Activated Resorcinol and AHA for optimal long-term stability and efficacy.

To achieve the most stable and effective formulation, it is best to select exfoliation ingredients known to be fully compatible with Activated Resorcinol and ensure the final formula pH is maintained within the 4.5-5.5 range.