Combining Different Molecular Weights of PolyGlutamic Acid
Question
I would like to ask if it is possible to use both molecular weights of PolyGlutamic Acid (High Molecule Weight and the other one) together in a formulation. If so, what percentage should I use for each, or what is the total percentage recommended?
Answer
Using Different Molecular Weights of PolyGlutamic Acid
Yes, you can use different molecular weights of PolyGlutamic Acid together in a formulation. Combining different molecular weights, such as High Molecule Weight, Low Molecule Weight, and Super Low Molecule Weight, can provide a more comprehensive range of benefits.
- High Molecular Weight: Tends to stay on the skin surface, providing excellent film-forming properties and immediate hydration, reducing transepidermal water loss.
- Low and Super Low Molecular Weight: Can penetrate the upper layers of the epidermis, offering hydration and potentially stimulating the skin's own moisturizing factors from within.
By using a blend, you can achieve both surface hydration and deeper moisture support.
Regarding the usage percentage, the recommended total usage rate for PolyGlutamic Acid (regardless of molecular weight or combination) is 0.1-1%, with 0.3-0.5% being the recommended range for general use. When combining different molecular weights, the sum of their percentages should not exceed the maximum recommended total (1%). For example, you could use 0.2% High MW and 0.2% Low MW for a total of 0.4%, which is within the recommended range.
