Combining Ethylbisiminomethylguaiacol Manganese Chloride (EUK-134) and ActiveProtec™ OX

Ethylbisiminomethylguaiacol Manganese Chloride (EUK-134) is indeed a powerful antioxidant known for its ability to scavenge free radicals and regenerate itself, making it excellent for anti-aging applications directly on the skin.

ActiveProtec™ OX, on the other hand, is a blend of antioxidants specifically designed to protect the formulation itself from oxidation and discoloration. It is particularly effective at stabilizing ingredients like certain whitening agents (Arbutin, Resorcinol, Vitamin C derivatives) and ingredients in hair removal formulas (thioglycolates) that are prone to color changes or degradation due to oxidation.

Therefore, while EUK-134 works to protect the skin, ActiveProtec™ OX works to protect the product's stability and appearance. You can use them together in a formulation, and it might be beneficial if your formula contains ingredients that ActiveProtec™ OX is known to stabilize.

Considerations for combining them:

• pH Compatibility: EUK-134 works best in a pH range of 6-8. ActiveProtec™ OX requires a pH above 4. If your formulation's pH is within the 6-8 range, they should be compatible.
• Purpose: If your formula contains ingredients prone to discoloration or oxidation (like Vitamin C or Arbutin), adding ActiveProtec™ OX alongside EUK-134 would be a good strategy to ensure both product stability and skin antioxidant benefits.

In summary, adding ActiveProtec™ OX is not strictly necessary for EUK-134 to function on the skin, but it can significantly improve the shelf-life and appearance of your cosmetic product, especially if it contains sensitive ingredients. Consider the other components of your formula and the target pH when deciding whether to include ActiveProtec™ OX.