Combining Hydro White and MSH White in Formulations

Yes, Hydro White (Hydroxyphenoxy Propionic Acid) and MSH White (Undecylenoyl Phenylalanine) can be used together in a cosmetic formulation.

Both ingredients are designed to address skin brightening through different mechanisms and are described as being compatible for use with other whitening substances. Hydro White works by inhibiting the release and transport of melanin pigment, while MSH White helps by reducing Alpha-MSH, a molecule that stimulates melanin production. Using them together can provide a more comprehensive approach to improving skin tone and reducing dark spots.

Formulation Considerations:

• Solubility: Hydro White is water-soluble and requires heating (60-80°C) to dissolve. MSH White is oil-soluble and requires heating (at least 60°C, recommended 80°C) to dissolve in the oil phase.
• Incorporation: In emulsion formulations (like creams or lotions), dissolve Hydro White in the water phase and MSH White in the oil phase, using heat as required for each, before combining the phases.
• Stability: Hydro White requires the addition of 1% ActiveProtec OX to the formula to help prevent discoloration.