Compatibility and Usage of PE-1 Aqua with Pentylene Glycol and 1,2-Hexanediol for Penetration Enhancement

Asked by: juron66 On: May 14, 2018 Product Type: Cosmetics Answered

Question

I would like to know about using PE-1 Aqua with Pentylene Glycol and 1,2-Hexanediol.

  • Can PE-1 Aqua be used together with Pentylene Glycol and 1,2-Hexanediol?
  • What is the recommended usage percentage for Pentylene Glycol or 1,2-Hexanediol when used for penetration enhancement, either alone or in combination with PE-1 Aqua?
  • Are there any potential issues, such as a "reservoir effect", if higher concentrations are used, and how does this affect the absorption efficiency of substances?

Answer

Based on the staff's reply, PE-1 Aqua can be used with both Pentylene Glycol and 1,2-Hexanediol.

However, it is important to note that the usage rate for Pentylene Glycol or 1,2-Hexanediol should be kept low, around 2-4%, when used for penetration enhancement (either alone or in combination with PE-1 Aqua). Using higher concentrations might cause a "reservoir effect" under the skin, potentially reducing the absorption efficiency.