Compatibility of Copper Peptide (GHK-Cu) and Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-Ake eq.)
คำถาม
I would like to know if [url=http://www.myskinrecipes.com/shop/%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%9B%E0%B9%84%E0%B8%97%E0%B8%94%E0%B9%8C%E0%B8%A5%E0%B8%94%E0%B8%A3%E0%B8%B4%E0%B9%89%E0%B8%A7%E0%B8%A3%E0%B8%AD%E0%B8%A2/272-copper-peptide-%E0%B8%84%E0%B8%AD%E0%B8%9B%E0%B9%80%E0%B8%9B%E0%B8%AD%E0%B8%A3%E0%B9%8C-%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%9B%E0%B9%84%E0%B8%97%E0%B8%94%E0%B9%8C-ghk-cu.html:2gxh88ak]Copper Peptide (GHK-Cu)[/url:2gxh88ak] can be mixed into a product containing (Syn-Ake eq.) [url=https://www.myskinrecipes.com/shop/%E0%B8%A2%E0%B8%81%E0%B8%81%E0%B8%A3%E0%B8%B0%E0%B8%8A%E0%B8%B1%E0%B8%9A%E0%B8%9C%E0%B8%B4%E0%B8%A7/7284-syn-ake-dipeptide-diaminobutyroyl-benzylamide-diacetate.html:2gxh88ak]Dipeptide Diaminobutyroyl Benzylamide Diacetate[/url:2gxh88ak]? Based on the information for [url=http://www.myskinrecipes.com/shop/%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%9B%E0%B9%84%E0%B8%97%E0%B8%94%E0%B9%8C%E0%B8%A5%E0%B8%94%E0%B8%A3%E0%B8%B4%E0%B9%89%E0%B8%A7%E0%B8%A3%E0%B8%AD%E0%B8%A2/272-copper-peptide-%E0%B8%84%E0%B8%AD%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%AD%E0%B8%A3%E0%B9%8C-%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%9B%E0%B9%84%E0%B8%97%E0%B8%94%E0%B9%8C-ghk-cu.html:2gxh88ak]Copper Peptide (GHK-Cu)[/url:2gxh88ak], it states that the formula [u:2gxh88ak]must not contain [url=http://www.myskinrecipes.com/shop/%E0%B8%AA%E0%B9%88%E0%B8%A7%E0%B8%99%E0%B8%9B%E0%B8%A3%E0%B8%B0%E0%B8%81%E0%B8%AD%E0%B8%9A%E0%B9%80%E0%B8%84%E0%B8%A3%E0%B8%B7%E0%B9%88%E0%B8%AD%E0%B8%87%E0%B8%AA%E0%B8%B3%E0%B8%AD%E0%B8%B2%E0%B8%87%E0%B8%84%E0%B9%8C/184-disodium-edta-2na.html:2gxh88ak]Disodium EDTA[/url:2gxh88ak] because [url=http://www.myskinrecipes.com/shop/%E0%B8%AA%E0%B9%88%E0%B8%A7%E0%B8%99%E0%B8%9B%E0%B8%A3%E0%B8%B0%E0%B8%81%E0%B8%AD%E0%B8%9A%E0%B9%80%E0%B8%84%E0%B8%A3%E0%B8%B7%E0%B9%88%E0%B8%AD%E0%B8%87%E0%B8%AA%E0%B8%B3%E0%B8%AD%E0%B8%B2%E0%B8%87%E0%B8%84%E0%B9%8C/184-disodium-edta-2na.html:2gxh88ak]Disodium EDTA[/url:2gxh88ak] will bind copper ions and reduce the effectiveness of [url=http://www.myskinrecipes.com/shop/%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%9B%E0%B9%84%E0%B8%97%E0%B8%94%E0%B9%8C%E0%B8%A5%E0%B8%94%E0%B8%A3%E0%B8%B4%E0%B9%89%E0%B8%A7%E0%B8%A3%E0%B8%AD%E0%B8%A2/272-copper-peptide-%E0%B8%84%E0%B8%AD%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%AD%E0%B8%A3%E0%B9%8C-%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%9B%E0%B9%84%E0%B8%97%E0%B8%94%E0%B9%8C-ghk-cu.html:2gxh88ak]Copper Peptide[/url:2gxh88ak][/u:2gxh88ak]. And (Syn-Ake eq.) [url=https://www.myskinrecipes.com/shop/%E0%B8%A2%E0%B8%81%E0%B8%81%E0%B8%A3%E0%B8%B0%E0%B8%8A%E0%B8%B1%E0%B8%9A%E0%B8%9C%E0%B8%B4%E0%B8%A7/7284-syn-ake-dipeptide-diaminobutyroyl-benzylamide-diacetate.html:2gxh88ak]Dipeptide Diaminobutyroyl Benzylamide Diacetate[/url:2gxh88ak] contains [url=https://www.myskinrecipes.com/shop/%E0%B8%AA%E0%B9%88%E0%B8%A7%E0%B8%99%E0%B8%9B%E0%B8%A3%E0%B8%B0%E0%B8%81%E0%B8%AD%E0%B8%9A%E0%B9%80%E0%B8%84%E0%B8%A3%E0%B8%B7%E0%B9%88%E0%B8%AD%E0%B8%87%E0%B8%AA%E0%B8%B3%E0%B8%AD%E0%B8%B2%E0%B8%87%E0%B8%84%E0%B9%8C/143-glycerin-%E0%B8%81%E0%B8%A5%E0%B8%B5%E0%B9%80%E0%B8%8B%E0%B8%AD%E0%B8%A3%E0%B8%B5%E0%B9%88%E0%B8%99.html:2gxh88ak]Glycerin[/url:2gxh88ak], AQUA, [url=https://www.myskinrecipes.com/shop/%E0%B8%A2%E0%B8%81%E0%B8%81%E0%B8%A3%E0%B8%B0%E0%B8%8A%E0%B8%B1%E0%B8%9A%E0%B8%9C%E0%B8%B4%E0%B8%A7/7284-syn-ake-dipeptide-diaminobutyroyl-benzylamide-diacetate.html:2gxh88ak]Dipeptide Diaminobutyroyl Benzylamide Diacetate[/url:2gxh88ak], and [u:2gxh88ak][url=http://www.myskinrecipes.com/shop/%E0%B8%AA%E0%B9%88%E0%B8%A7%E0%B8%99%E0%B8%9B%E0%B8%A3%E0%B8%B0%E0%B8%81%E0%B8%AD%E0%B8%9A%E0%B9%80%E0%B8%84%E0%B8%A3%E0%B8%B7%E0%B9%88%E0%B8%AD%E0%B8%87%E0%B8%AA%E0%B8%B3%E0%B8%AD%E0%B8%B2%E0%B8%87%E0%B8%84%E0%B9%8C/184-disodium-edta-2na.html:2gxh88ak]Disodium EDTA[/url:2gxh88ak][/u:2gxh88ak]. My questions are: 1. Does this mean these two specific ingredients cannot be included in the same formula? 2. The website mentions The Ordinary "Buffet" + [url=http://www.myskinrecipes.com/shop/%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%9B%E0%B9%84%E0%B8%97%E0%B8%94%E0%B9%8C%E0%B8%A5%E0%B8%94%E0%B8%A3%E0%B8%B4%E0%B9%89%E0%B8%A7%E0%B8%A3%E0%B8%AD%E0%B8%A2/272-copper-peptide-%E0%B8%84%E0%B8%AD%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%AD%E0%B8%A3%E0%B9%8C-%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%9B%E0%B9%84%E0%B8%97%E0%B8%94%E0%B9%8C-ghk-cu.html:2gxh88ak]Copper Peptide[/url:2gxh88ak]s 1% contains (Syn-Ake eq.) [url=https://www.myskinrecipes.com/shop/%E0%B8%A2%E0%B8%81%E0%B8%81%E0%B8%A3%E0%B8%B0%E0%B8%8A%E0%B8%B1%E0%B8%9A%E0%B8%9C%E0%B8%B4%E0%B8%A7/7284-syn-ake-dipeptide-diaminobutyroyl-benzylamide-diacetate.html:2gxh88ak]Dipeptide Diaminobutyroyl Benzylamide Diacetate[/url:2gxh88ak] in its formula. Does this mean they can be included, or is it a different type of [url=http://www.myskinrecipes.com/shop/%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%9B%E0%B9%84%E0%B8%97%E0%B8%94%E0%B9%8C%E0%B8%A5%E0%B8%94%E0%B8%A3%E0%B8%B4%E0%B9%89%E0%B8%A7%E0%B8%A3%E0%B8%AD%E0%B8%A2/272-copper-peptide-%E0%B8%84%E0%B8%AD%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%AD%E0%B8%A3%E0%B9%8C-%E0%B9%80%E0%B8%9B%E0%B9%8A%E0%B8%9B%E0%B9%84%E0%B8%97%E0%B8%94%E0%B9%8C-ghk-cu.html:2gxh88ak]Copper Peptide[/url:2gxh88ak]? Thank you.
คำตอบ
Compatibility of Copper Peptide (GHK-Cu) and Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-Ake eq.)
Based on the information available for the specific ingredients sold, you are correct in your observation.
Can these two ingredients be used in the same formula?
The description for Copper Peptide (GHK-Cu) explicitly states that the formula should not contain Disodium EDTA because it will bind the copper ions and reduce the effectiveness of the Copper Peptide. The ingredient list for Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-Ake eq.) sold includes Disodium EDTA.Therefore, based on the provided ingredient information, these two specific ingredients cannot be effectively combined in the same formula due to the presence of Disodium EDTA in the Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-Ake eq.) product.
Regarding The Ordinary "Buffet" + Copper Peptides 1% example:
It is true that The Ordinary product is mentioned as an example formulation for both Copper Peptide (GHK-Cu) and Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-Ake eq.). However, this specific example refers to a finished commercial product. While that product does contain both types of peptides, the specific Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-Ake eq.) ingredient sold here contains Disodium EDTA, making it incompatible with Copper Peptide according to the Copper Peptide's usage instructions.Commercial formulations can be complex and may use different forms of ingredients or chelating agents, or employ specific formulation techniques to manage potential incompatibilities. However, when using the raw ingredients as sold here, the incompatibility due to Disodium EDTA in the Syn-Ake eq. ingredient must be respected to maintain the efficacy of the Copper Peptide.
In summary, while a commercial product might contain both, the specific raw materials you are asking about are incompatible if the Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-Ake eq.) ingredient contains Disodium EDTA, as is stated in its description.
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