Compatibility of Ingredients from Two Formulations

Subject: Ingredient Compatibility

Mixing cosmetic ingredients from different formulations requires careful consideration, as interactions between ingredients can affect stability, efficacy, and safety.

The ingredients you listed from the two formulas include:

• From Formula 1: Plankton Artemia Extract, Creatine 100, Vitamin B3 (Niacinamide), Sodium Lactate Plus, Pitera (Galactomyces Ferment Filtrate)
• From Formula 2: DMAE, Copper Peptide, Vitamin B5 (Panthenol), MOIST24 (Glycereth-26), Pitera (Galactomyces Ferment Filtrate)

Combining all these ingredients, especially at the concentrations mentioned, presents potential compatibility challenges:

1. Niacinamide (Vitamin B3) and Copper Peptide: High concentrations of Niacinamide can potentially interact with Copper Peptide, especially depending on the overall pH of the mixture. This can sometimes lead to degradation of one or both ingredients or the formation of Niacin, which can cause skin flushing or irritation.
2. DMAE and Copper Peptide: DMAE is an amine and can increase the pH of a formulation. Copper Peptide is sensitive to high pH and can precipitate or lose efficacy in alkaline environments. Combining these two ingredients requires careful pH control.

Simply mixing these ingredients together without proper formulation expertise, pH adjustment, and stability testing is not recommended. There is a significant risk that the ingredients may degrade, lose their intended benefits, or potentially cause adverse skin reactions.

For complex combinations of active ingredients like these, it is best to consult with a cosmetic formulator or follow professionally developed recipes that have undergone stability and compatibility testing.