Compatibility of Magnesium Ascorbyl Phosphate (MAP) and Niacinamide in Serum
คำถาม
Regarding a serum containing the following ingredients:
- Magnesium Ascorbyl Phosphate (MAP)
- Niacinamide (Vitamin B3)
Can these ingredients be mixed in the same formulation?
I have read that Vitamin C should not be mixed with B3 in a formulation, so I am unsure. However, many serum brands contain both Vitamin C derivatives (MAP) and B3 in the same formula.
I would like to understand for my knowledge whether these can be mixed in the same serum formulation and if there are any side effects.
คำตอบ
Subject: Regarding Vit C (MAP) + Niacinamide
Hello,
Thank you for your question. It's a common concern regarding the combination of Vitamin C and Niacinamide.
The concern about mixing Vitamin C and Niacinamide primarily applies to L-Ascorbic Acid (pure Vitamin C) at low pH levels. Under these conditions, L-Ascorbic Acid can react with Niacinamide to form Niacin (Nicotinic Acid), which can cause temporary skin flushing and redness.
However, Magnesium Ascorbyl Phosphate (MAP) is a stable derivative of Vitamin C. Unlike L-Ascorbic Acid, MAP is water-soluble and typically formulated at a higher, skin-friendly pH (around 6-7). Niacinamide is also stable and effective in this pH range.
Therefore, Magnesium Ascorbyl Phosphate (MAP) and Niacinamide are generally compatible and can be safely formulated together in a serum. Many commercial products successfully combine these two ingredients to leverage their synergistic benefits, such as antioxidant protection, skin brightening, and improving skin barrier function.
When formulated correctly at the appropriate pH, combining MAP and Niacinamide should not cause significant side effects. However, as with any skincare product, individual skin sensitivity can vary.
We hope this clarifies your query.
ผลิตภัณฑ์ที่เกี่ยวข้องที่กล่าวถึง
Safe-B3™ (Vitamin B3, Niacinamide)
