Formulation and Preservative Recommendations for Children with Atopic Skin

Based on your request for a cream or lotion formulation for children with atopic skin and a gentle preservative, here is some information and product recommendations.

It's important to remember the previous advice to consult a dermatologist for appropriate medical treatment for atopic dermatitis. The information below focuses on ingredients and preservatives that are generally considered gentle and suitable for sensitive skin.

For a formulation aimed at soothing and moisturizing atopic skin, consider incorporating ingredients known for their calming and skin-barrier supporting properties:

• Oat Derivatives: Ingredients like Oat Avenanthramides or ActiveRelease Oat (Hydroxyphenyl Propamidobenzoic Acid) are known for their ability to reduce itching and redness, which are common symptoms of atopic skin.
• Soothing Agents: Bisabolol, found in chamomile, is another ingredient recognized for its anti-irritant properties.
• Emollients/Oils: Babassu Oil is a natural moisturizer that is quickly absorbed and suitable for dry, itchy skin and eczema.

When selecting a preservative for a product intended for sensitive or atopic skin, mildness is key. Several options are designed to be gentle:

• Mild Preserved Eco (Ethylhexylglycerin, 1,3 Propanediol): This blend is described as gentle and non-irritating, and is not classified as a preservative by the FDA, allowing for "preservative-free" claims. It also has humectant properties.
• Preserve-Free BHL (Caprylhydroxamic Acid, 1,2-Hexanediol, Butylene Glycol): Similar to Mild Preserved Eco, this is presented as a highly effective yet gentle option that is not classified as a preservative by the FDA.
• Mild Preserved CGZ (similar composition to Mild Preserved Eco): Another gentle, non-irritating option with a wide pH range suitability.
• Mild Preserved COS (Phenoxyethanol, Chlorphenesin, Caprylyl Glycol): A broad-spectrum preservative that is water-soluble and odorless, suitable for a wide pH range.
• NaturePreserve LB2 (Dehydroacetic Acid, Benzoic Acid, Benzyl Alcohol, Water): A natural origin option effective against bacteria and fungi, particularly at lower pH values.

When formulating, always perform a challenge test to ensure the chosen preservative system is effective for your specific formula.

Here is a summary of recommended products:

• Soothing/Moisturizing Ingredients: Oat Avenanthramides, ActiveRelease Oat, Bisabolol, Babassu Oil.
• Mild Preservatives: Mild Preserved Eco, Preserve-Free BHL, Mild Preserved CGZ, Mild Preserved COS, NaturePreserve LB2.

Remember to always start with a simple base formulation suitable for sensitive skin and gradually add active ingredients. Consulting with a cosmetic chemist experienced in formulating for sensitive skin is also highly recommended.