Formulation of Healing Wound Serum with Nano Silver and Panthenol

Asked by: sequinn347 On: April 10, 2026 Product Type: Cosmetics Answered

Question

Hi, to make a Healing Wound Serum with your 2000ppm Colloidal Yellow solution test batch of total 25mls product, could I use the following:

Ingredient Actual Grams %
Distilled Water (NDA) 23.3g 92.00%
Nano Colloidal Silver 2000pm solution (Water Soluble) 0.5g 2.00%
Glycerine or Hyaluronic Acid 1.3g 5.00%
Panthanol Vitamin 5 0.5g 1%
Total 25mls

Or is adding Pananthol a waste of time and just stick to the other 3 ingredients? If not, what do you suggest? It is for home use, not for sale. Many thanks.

Answer

Ingredient Status & Resolution

Before we dive into your formula, here is the status of the ingredients you requested from our catalog:

  • Nano Silver (2000ppm, Colloidal, Yellow Solution): Found.
  • Distilled Water (NDA): Not Found. While we do not carry the "NDA" brand specifically, you can use any high-quality Distilled Water as the base for your serum.
  • Glycerine: Found.
  • Hyaluronic Acid: Found.
  • Panthenol (Vitamin B5): Found.

Is Panthenol a "waste of time"?

No, it is highly recommended. Panthenol (Pro-Vitamin B5) is a powerhouse for a healing serum. It is clinically recognized for its ability to:

  • Accelerate Wound Healing: It promotes skin cell proliferation, helping the skin repair itself faster.
  • Reduce Inflammation: It effectively calms redness and irritation.
  • Strengthen the Skin Barrier: It helps prevent moisture loss during the healing process.

Critical Stability Warning: Nano Silver vs. Hyaluronic Acid

There is a technical conflict in your proposed list:

  • Colloidal Nano Silver is extremely sensitive to electrolytes (salts).
  • Most Hyaluronic Acid (Sodium Hyaluronate) is a salt. Adding it to the Nano Silver solution can cause the silver particles to aggregate (clump), which may lead to discoloration (turning grey/black) and a loss of antimicrobial effectiveness.
  • Recommendation: Use Glycerin instead of Hyaluronic Acid. Glycerin is non-ionic and will not interfere with the stability of the colloidal silver.

Suggested Healing Serum Formula (25g Batch)

To ensure stability and maximum healing benefit, here is a balanced version of your recipe:

Ingredient Grams % Purpose
Distilled Water 23.00g 92% Base Solvent
Nano Silver (2000ppm) 0.50g 2% Antimicrobial / Disinfectant
Glycerin 1.25g 5% Non-ionic Moisturizer
Panthenol (Vitamin B5) 0.25g 1% Healing & Regeneration
Total 25.00g 100%

Mixing Instructions

  1. Dissolve: Add the Panthenol powder to the Distilled Water and stir until completely clear.
  2. Hydrate: Add the Glycerin and stir until uniform.
  3. Active: Add the Nano Silver (2000ppm) last. Stir gently.
  4. pH Check: Ensure the final pH is between 6.0 and 7.0. This range is optimal for both Nano Silver stability and Panthenol effectiveness.
  5. Storage: Store in an amber or opaque bottle away from direct sunlight, as Nano Silver is light-sensitive.
  • Note: Since this formula is 92% water, if you plan to keep it for more than a few days, you should add a preservative (like Phenoxyethanol at 1%) to prevent microbial growth.*

Tags

Active Ingredient Combination Active Ingredient Stability Antimicrobial Serum Wound Healing