How to Dissolve Hyaluronic Acid Powder

Question

I would like to know the detailed methods for dissolving Hyaluronic Acid powder in water, covering both scenarios:

Without a blender: What is the step-by-step process, including mixing, shaking, and refrigeration times?
With a blender: What blending speed (e.g., 1,000 rpm) and powder addition technique are recommended?

Additionally, what are the crucial precautions to observe regarding:

The optimal pH range (3.0-9.0) for maintaining Hyaluronic Acid quality?
The maximum temperature (not exceeding 70 degrees Celsius) during mixing?
The importance of adding a preservative (such as Phenoxyethanol) to prevent bacterial degradation and loss of gel viscosity?

MySkinRecipes Expert · Accepted Answer

How to Dissolve Hyaluronic Acid Powder

Hyaluronic Acid powder can be dissolved in cold water using the following mixing methods:

If You Do Not Have a Blender

Mix the Hyaluronic Acid powder before adding any other liquid ingredients, but after all dry powder ingredients.
Gradually add the Hyaluronic Acid powder to the water (water-phase).
Close the container and shake vigorously for 1-3 minutes.
Refrigerate for at least 3 hours to allow the powder to dissolve.
Take it out and check the product texture. If it is not completely dissolved, shake again and continue refrigerating until you observe that the powder has completely dissolved with no sediment or floating powder.

If You Have a Blender

Blend the water at a speed of at least 1,000 rpm.
Gently sprinkle the Hyaluronic Acid powder onto the water surface little by little continuously while blending until combined.

Precautions:

To maintain the quality of Hyaluronic Acid, the pH must be between 3.0-9.0.
The temperature should not exceed 70 degrees Celsius during mixing.
Always add a preservative such as Phenoxyethanol. Without preservatives, bacteria will destroy the Hyaluronic molecules, causing the resulting gel texture to lose viscosity within a few days.

If it is not convenient to dissolve Hyaluronic Acid powder in water, you can choose to use Liquid Hyaluronic Acid, which dissolves immediately in water.