Ingredient Compatibility and Mixing Method

Yes, the ingredients you listed are generally compatible and can be mixed together to create a water-based serum or gel formulation.

Here are the ingredients:

• Glycerin
• Safe-B3 (Niacinamide / Vitamin B3)
• GlucoBright (N-Acetyl Glucosamine)
• Mild Preserved Eco (Ethylhexylglycerin, 1,3 Propanediol)
• AnyGel (Dehydroxanthan Gum)
• Water

These ingredients are all water-soluble or dispersible in water, making them suitable for a single-phase aqueous formulation.

Recommended Mixing Method

A cold process method is recommended to protect the ingredients, especially Safe-B3 and GlucoBright, which should not be heated for prolonged periods, and Mild Preserved Eco, which has a heat limit.

1. Prepare the Water Phase: Start with the required amount of water in a mixing container.
2. Dissolve Water-Soluble Ingredients: Add Glycerin, Safe-B3, and GlucoBright to the water. Stir or mix thoroughly until all powders are completely dissolved. Gentle warming (below 40°C) can be used if needed to help dissolution, but avoid prolonged heat.
3. Hydrate the Thickener: Slowly sprinkle AnyGel powder onto the surface of the water phase while mixing continuously. Mix vigorously (using a homogenizer or high-shear mixer if available, or a strong stirrer) for sufficient time to allow the AnyGel to fully hydrate and thicken the mixture into a smooth gel. Avoid adding the powder too quickly, as this can cause clumping.
4. Add Preservative: Once the gel is uniform and smooth, add Mild Preserved Eco. Mix well to ensure it is evenly distributed throughout the gel.
5. Adjust pH (if necessary): Check the pH of the final formulation. Safe-B3 works best in the pH range of 4.0-7.0, GlucoBright in 3-7, and Mild Preserved Eco in 4-9. Aim for a final pH between 4.0 and 7.0 for optimal performance and stability of all ingredients and good skin compatibility. Adjust with a suitable acid or base if needed.
6. Final Mixing: Continue mixing for a few more minutes to ensure homogeneity.

This method will allow you to create a stable and effective product using these ingredients.