Ingredient Compatibility Check

Based on the ingredients you've listed:

• Licorice
• Gluco Bright
• Extreme- B3
• Glass Moist
• Witch Hazel
• Allantoin 0.5%
• Vit E
• MOIST24
• Phenoxyethanol SA (eq. Optiphen Plus) 1%
• Disodium EDTA 0.2%
• Purified Water

Most of these ingredients are water-soluble or dispersible and can be combined in a water-based formulation. We have found information on specific products that match your list, including Licorice Extract (Water-Soluble), GlucoBright (Acetyl Glucosamine), Extreme-B3 (Niacinamide), Glass Moist, Witch Hazel (Distillate), Allantoin, MOIST24, Phenoxyethanol SA, Disodium EDTA, and Vitamin E (Tocopheryl Acetate).

Here are the key compatibility considerations:

• Vitamin E (Tocopheryl Acetate): This form of Vitamin E is oil-soluble. In a mostly water-based formula like yours, it will not dissolve and will separate unless you include an emulsifier or solubilizer to properly incorporate the oil phase into the water phase.
• Preservative pH: Phenoxyethanol SA (Optiphen Plus) is effective within a pH range of 2.0-6.0. The pH ranges of the other ingredients (GlucoBright, Extreme-B3, Witch Hazel, Allantoin, MOIST24, Disodium EDTA) are generally compatible with this, but you must check the final pH of your mixture and adjust it to be within the 2.0-6.0 range (ideally 3.0-6.0) to ensure the preservative works correctly.
• Mixing Procedure: Some ingredients like Witch Hazel, Licorice Extract, Glass Moist, and Phenoxyethanol SA are sensitive to heat and should be added in the final cooling phase (below 40-60°C). Allantoin dissolves better in warm water, but at your proposed 0.5% concentration, it should dissolve at room temperature according to product information. Disodium EDTA should be added to the water phase early.
• Storage: Glass Moist requires refrigeration for long-term storage. Therefore, the final product containing Glass Moist should also be stored in the refrigerator.

In summary, while most ingredients are compatible, the oil-soluble Vitamin E (Tocopheryl Acetate) will require an emulsifier or solubilizer for proper incorporation into your water-based formula. You must also check and adjust the final pH to ensure the preservative is effective and store the final product in the refrigerator.