Ingredient Substitution Guidance

Here is information regarding potential substitutions for the ingredients you asked about:

Silicone Quaternium-22

Silicone Quaternium-22 and Quaternium-75 are different types of ingredients with distinct chemical structures and functions. Therefore, Quaternium-75 is generally not a direct substitute for Silicone Quaternium-22.

Based on searches for related ingredients:

• Silicone Quaternium-16 (available as Micro-Quat16™) is a silicone-based hair conditioner known for making hair soft.
• Quaternium-73 (available as Quaternium-73) is primarily used for its antiseptic properties against bacteria like P. acnes and can help reduce melanin formation.
• Polyquaternium-47 (available as Poly-Conditioner 47) and Polyquaternium-28 (available as Poly-Conditioner 28) are general hair and skin conditioners that improve manageability and feel.

Given these different functions, substituting Silicone Quaternium-22 would require understanding its specific role in your formulation (e.g., conditioning, emulsification, texture) and finding an alternative ingredient with similar properties, which may not be Quaternium-75 or the related Quaternium/Polyquaternium compounds found.

Isostearamide MIPA

Isostearamide MIPA is often used as a surfactant, emulsifier, or thickener. A potential substitute to consider is Stearamidopropyl Dimethylamine.

• Stearamidopropyl Dimethylamine is used as a co-emulsifier and conditioner in skin and hair formulations. It has a positive charge that helps it adhere to hair and skin.

Keep in mind that Stearamidopropyl Dimethylamine has specific pH requirements (pH 5.5-6.5 in the water phase) during the emulsification process, which might require adjustments to your formulation method.

Glyceryl Laurate

Glyceryl Laurate is also known as Glyceryl Monolaurate or Monolaurin. This ingredient has antiseptic properties and acts as a co-emulsifier, commonly used in products like deodorants.

If you are looking for alternatives, consider the primary function you need:

• For Antiseptic and Co-emulsifying properties: Glyceryl Monolaurate (Glyceryl Laurate, Monolaurin) is the same ingredient and provides these benefits.
• For Emulsifying properties: Other emulsifiers like Polyglyceryl-3 Laurate, Polyglyceryl-4 Laurate, or Polyglyceryl-6 Laurate could potentially be used. However, these are typically water-in-oil emulsifiers with different HLB values and solubility profiles (soluble in oil) compared to Glyceryl Monolaurate (dispersible in water). Substituting with these would require significant formulation adjustments.

Choosing the best substitute depends on the specific role each ingredient plays in your original formula.