Understanding Kaempferol Solubility in Water-Based Formulas

Based on your experiment, dissolving Pure-Kaempferol™ (98%) in alcohol first and then adding water causes turbidity and separation. This is a common issue with ingredients that are not highly water-soluble.

1. Making a Clear Water-Based Product (Toner/Essence):

   • Pure-Kaempferol™ (98%) is soluble in ethanol but has limited solubility in water. When you add water to the alcohol solution, the overall polarity changes, reducing the solubility of Kaempferol and causing it to come out of the solution.
   • Increasing the alcohol ratio might help keep it dissolved, but this can make the product drying or irritating for the skin, which might not be suitable for a toner/essence.
   • To incorporate Kaempferol clearly into a water-based product, you would typically need to use a suitable solubilizer or dispersant. However, even with solubilizers, achieving perfect clarity can be challenging depending on the concentration.
   • An alternative specifically designed for this purpose is Micromul™ Kaempferol (Microemulsion Kaempferol). This product is Kaempferol already processed into a microemulsion form, making it easily soluble in water and suitable for clear, watery formulations like toners or essences. It also offers enhanced skin absorption compared to the standard powder form.

2. Is Turbidity/Separation Precipitation?

   • Yes, the cloudiness and subsequent separation you observe indicate that the Kaempferol is precipitating or coming out of the solution because it is no longer soluble in the water/alcohol mixture at that concentration.

3. Can the Cloudy Mixture Be Used? Is it Absorbable?

   • While you could potentially use the cloudy mixture by shaking it before each use, the Kaempferol is present as undissolved particles. Undissolved ingredients are generally not absorbed by the skin as effectively as dissolved ingredients.
   • Therefore, using the cloudy mixture might result in reduced efficacy compared to a formulation where the Kaempferol is properly dissolved or dispersed in a way that allows for better skin penetration, such as using Micromul™ Kaempferol.

For a clear, water-based product like a toner or essence with good absorption, Micromul™ Kaempferol is a more suitable option as it is designed to be water-soluble and enhance skin penetration.