Mixing Ectoine and EGF in Hyaluronic Serum

Yes, you can mix Ectoine and EGF into a hyaluronic serum, but there are specific considerations for each ingredient to ensure stability and effectiveness.

Here's a breakdown:

• Ectoine: This ingredient is highly stable and water-soluble. It can be dissolved in the water phase of your serum and can withstand a wide pH range (1-9) and temperatures up to 80°C. It is generally easy to incorporate into most water-based formulations like hyaluronic acid serums.

• EGF (Epidermal Growth Factor): EGF is also water-soluble, but it is more sensitive to temperature and pH. For best stability, it should be added at the final step of your formulation process, when the temperature is below 40°C (ideally around 25°C). The optimal pH range for EGF stability is between 3 and 5. While you can add it to a hyaluronic serum with a slightly higher pH, its stability might be reduced over time.

Mixing Instructions:

1. Prepare your hyaluronic acid serum base.
2. Add Ectoine to the water phase and ensure it is fully dissolved.
3. Once the serum base is complete and has cooled to below 40°C (preferably room temperature), add the EGF.
4. Gently mix until the EGF is completely dissolved.
5. Ideally, check and adjust the final pH of the serum to be between 3 and 5 for optimal EGF stability.

By following these steps, you can effectively combine Ectoine and EGF in your hyaluronic serum.