PE-1 Aqua: Properties, Usage, and Alternatives for Penetration Enhancement
Question
Could you please provide detailed information about the ingredient PE-1 Aqua, including its function as a penetration enhancer for water-soluble active ingredients, its composition, physical characteristics, solubility, recommended usage rate (especially for eye area products), important usage considerations (compatibility with chemical sunscreens and other penetration enhancers, suitability for oil-soluble actives), INCI name, storage conditions, shelf life, and potential alternative ingredients like Phospholipid, Laurocapram, 1,2-Hexanediol, Ethoxydiglycol, or Reservoir-Tech?
Answer
About PE-1 Aqua
Based on the information available, I can provide details about PE-1 Aqua, although I cannot give you an exact restock date. The previous staff reply indicated an expected timeline, but I cannot provide an updated status.
PE-1 Aqua is a penetration enhancer designed to help water-soluble active ingredients penetrate the skin more effectively. It is composed of natural terpenes, including Eucalyptol (1,8-cineole), which is known for its high penetration-enhancing properties.
Here are some key details about PE-1 Aqua:
- Function: Enhances the penetration of water-soluble active ingredients into the skin by 2-20 times compared to formulations without it.
- Composition: Made from natural terpenes found in essential oils.
- Appearance: Clear liquid with a mild natural scent similar to Eucalyptus. It is non-comedogenic.
- Solubility: Oil-soluble. It should be mixed into the oil phase of a formulation.
- Recommended Usage Rate: 1.5-3.5%. For products around the eye area, a lower rate of 1.0-2.0% is recommended. Using more than the recommended amount can actually decrease penetration efficiency.
- Important Considerations:
- Do not use PE-1 Aqua in formulations containing chemical sunscreens, as enhanced penetration of chemical sunscreens can be harmful.
- Using PE-1 Aqua with other penetration enhancers (except Pentylene Glycol, which can work synergistically) may reduce its effectiveness.
- PE-1 Aqua is designed for water-soluble actives. Using it with oil-soluble actives will reduce the absorption efficiency of the oil-soluble actives.
- INCI Name: Fragrance (due to its composition from natural terpenes commonly used in fragrances).
- Storage: Store at room temperature, tightly sealed, and away from sunlight or heat. It has a shelf life of at least 2 years.
If PE-1 Aqua is not suitable for your formulation (e.g., if you are using oil-soluble actives), alternatives like Phospholipid (Hydrogenated Lecithin) are suggested. Other penetration enhancers mentioned include Laurocapram (for water-soluble actives, synthetic, mild odor), Phospholipid (for both water and oil-soluble actives, natural origin but chemically modified, good skin feel, moisturizing), 1,2-Hexanediol (can enhance penetration when used with others, also acts as a preservative, solvent, and humectant), and Ethoxydiglycol (can enhance penetration when used with others, also acts as a solvent). Reservoir-Tech is mentioned as a film-forming ingredient that helps store and slowly release actives, which can reduce irritation for ingredients like AHA/BHA, but it is not a direct penetration enhancer like PE-1 Aqua.
For the most current information on availability, please continue to check the product page or contact customer service directly.
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