Penetration Enhancer Solubility: DMI vs Phospholipid

Asked by: sangchai1 On: March 10, 2020 Product Type: Cosmetics

Question

I want to confirm if Dimethyl Isosorbide (DMI) primarily carries ingredients that are dissolved in water, oil, or both? I saw in a previous post that Phospholipid was recommended if the ingredients are dissolved in both water and oil. Thank you in advance.

Answer

Based on the product information:

  • Dimethyl Isosorbide (DMI) is primarily suitable for carrying ingredients that are dissolved in water. While it can dissolve in some oils and silicones, its main function as a penetration enhancer is for water-soluble active ingredients.
  • Phospholipid is suitable for carrying both water-soluble and oil-soluble ingredients. For Phospholipid to be incorporated, the formula must contain both water and oil phases.

Therefore, your understanding from the previous post is correct. If your formulation contains active ingredients that are dissolved in both water and oil phases, Phospholipid is a suitable choice as a carrier for both types.

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