Penetration Enhancers for Oil-Soluble Ingredients and Mixed Formulas
Asked by: shoppingist
On: October 27, 2018
Product Type:
Cosmetics
Question
Regarding penetration enhancers:
- Can 1,2-Hexanediol and Pentylene Glycol enhance the penetration of oil-soluble ingredients?
- If they cannot enhance the penetration of oil-soluble ingredients like Dimethyl Isosorbide (DMI), can 1,2-Hexanediol, Pentylene Glycol, or Dimethyl Isosorbide (DMI) be included in a formula containing both water-soluble and oil-soluble ingredients without inhibiting the absorption of the oil-soluble components?
Answer
Based on the information provided:
- Regarding 1,2-Hexanediol and Pentylene Glycol, there is no clear research confirming their ability to enhance the penetration of oil-soluble ingredients. For carrying oil-soluble ingredients, Phospholipid is recommended.
- If Dimethyl Isosorbide (DMI), 1,2-Hexanediol, or Pentylene Glycol are used in a formula containing both water-soluble and oil-soluble ingredients:
- DMI is primarily suitable for water-soluble ingredients, with variable results for oil-soluble ones.
- 1,2-Hexanediol and Pentylene Glycol lack clear evidence for enhancing oil-soluble penetration.
- Using these ingredients in a mixed formula may not necessarily inhibit the absorption of oil-soluble ingredients, but they will not actively enhance it.
- For formulas containing both water and oil-soluble ingredients, Phospholipid is recommended as it has research and a history of effectively carrying various types of ingredients, offering a more reliable penetration enhancement for the overall formula.
