Preservatives for Water-Based Mouthwash

Based on your question about suitable preservatives for a water-based mouthwash formulation and the staff's recommendation, Global Guard™ is a suitable option.

Global Guard™ is preferred for oral care products because its main components, Sodium Benzoate and Potassium Sorbate, are commonly used in food. It is effective at a concentration of 1.0-1.5% but is limited to formulations with a pH less than 5.5.

An alternative is Global Guard™ 221 (pH 2-7, Natural), which is a water-soluble, broad-spectrum preservative that works effectively in a wider pH range of 2-7 and is globally approved. It is used at a rate of 0.5-1.1% and should be added at temperatures below 45°C.

When formulating, remember to consider the pH of your final product to choose the most effective preservative. As the staff mentioned, more ingredients for oral care will be available soon, which may offer additional options for your formulation.