Retinyl Palmitate: Form, Solubility, Concentration, and Stability

Regarding your questions about Retinyl Palmitate:

1. Yes, the Retinyl Palmitate product refers to All-trans Retinyl Palmitate. The cis form indicates degraded Retinyl Palmitate, often due to exposure to UV light or high temperatures.
2. The product is soluble in most oils. However, the staff does not have specific information regarding its effect on liposome preparation or the exact type of oil and its proportion in the 20g and 100g product sizes.
3. Your understanding of the concentration and conversion seems correct based on the provided information. The concentration is 1.7 Million IU per gram of product. Using the conversion factor where 3.33 IU is equivalent to 1 microgram of retinol, 1 gram of the product provides the activity equivalent to approximately 0.51 grams of retinol (1,700,000 IU / 3.33 IU/µg = 510,510.51 µg = 0.51051 g). This calculation helps you determine the amount of product needed to achieve a desired retinol equivalent concentration in your formulation.
4. No, the product may not always be a homogenous liquid without precipitate. Temperature changes can cause precipitation, which is a natural characteristic of Retinyl Palmitate. You should warm the product to dissolve any precipitate and ensure it is homogenous before using it in your formulation.