Skin Irritation from Cosmetic Formulation Ingredients
Question
I have a cosmetic formulation containing the following ingredients:
- Myristyl Nicotinate (Pro-Niacin™)
- Yeast Radiance™
- Copper Peptide (GHK-Cu)
- Centella Asiatica Extract (Madecassoside)
- Hi-EGCG™ (Green Tea Extract)
- Apple Stem Cell Extract (AppleCell™)
- RETINAT™ (Starfish Extract)
- Rosa Hybrid Cell Extract (HybridCell™)
After using this formulation, I experienced stinging, redness, and irritation. Which of these ingredients is most likely causing this reaction?
Answer
Potential Irritants in Your Formulation
Based on your experience of stinging, redness, and irritation after using your formulation, and the feedback from our staff, the most likely ingredient causing this reaction is Myristyl Nicotinate (Pro-Niacin™). Our staff has noted that approximately 5-10% of users experience irritation from this ingredient.
Myristyl Nicotinate, also known as Max-B3™, is an oil-soluble form of Vitamin B3. While it offers several benefits such as improving skin barrier function, reducing wrinkles, and enhancing skin tone and texture, it is known to cause a warming or flushing sensation and potential irritation in some sensitive individuals.
Regarding the other ingredients you listed:
- Yeast Radiance™: This is a yeast protein extract intended to brighten the skin without causing irritation.
- Copper Peptide (GHK-Cu): This peptide is used for anti-aging, scar reduction, and stimulating hair growth. Its description does not indicate irritation as a common side effect.
- Centella Asiatica Extract (Madecassoside): This extract is known for its soothing and anti-inflammatory properties, helping to reduce redness and promote skin healing. It is generally well-tolerated.
- Hi-EGCG™ (Green Tea Extract): This extract is a powerful antioxidant with anti-inflammatory and anti-acne properties. It is typically soothing to the skin.
- Apple Stem Cell Extract (AppleCell™): This extract is used for its anti-aging benefits and to help skin cells last longer. It is not commonly associated with irritation.
- RETINAT™ (Starfish Extract): This ingredient is designed to provide benefits similar to retinoids (like reducing wrinkles and improving skin firmness) but without the typical irritation associated with Vitamin A derivatives.
- Rosa Hybrid Cell Extract (HybridCell™): Derived from pink rose stem cells, this extract helps stimulate collagen and improve skin elasticity and texture. It is not generally known to cause irritation.
While Myristyl Nicotinate is the most probable cause based on the information, it's important to remember that individual skin sensitivity varies, and a reaction to any ingredient is possible. If you continue to experience irritation, you may consider removing Myristyl Nicotinate from your formulation or reducing its concentration.
Related Products Mentioned
Hi-EGCG™ (Green Tea Extract)
Rosa Hybrid Cell Extract (HybridCell™)
RETINAT™ (Starfish Extract)