Solubility issue of Activated Resorcinol in water-based product

ถามโดย: non.ant เมื่อ: October 28, 2021 ประเภทผลิตภัณฑ์: เครื่องสำอาง

คำถาม

I tested dissolving Activated Resorcinol(TM) in Butylene Glycol and found it dissolved well and was clear. In this step, it was fine. However, when I mixed it with a water-based ingredient (I mixed it into Malissa Kiss AloeVera 99.5%), it turned into a milky white liquid, similar to milk. Is this normal? Or is the dissolution incomplete in step 2? I would like some advice.

คำตอบ

Based on your description, it sounds like the Activated Resorcinol (4-Butylresorcinol) is precipitating out of the solution when you mix it with the water-based product (Malissa Kiss AloeVera 99.5%).

Here's a breakdown:

  1. Dissolving in Butylene Glycol: Activated Resorcinol is soluble in Butylene Glycol, which is why your initial mixture was clear. Butylene Glycol acts as a good solvent for it.
  2. Mixing with Water-Based Product: Activated Resorcinol (4-Butylresorcinol) has limited solubility in water. When you added the water-based product (which is primarily water), the overall solvent system in your mixture became much more aqueous. This reduced the solubility of the Activated Resorcinol, causing it to come out of the solution and form very fine solid particles suspended in the liquid. These fine particles scatter light, making the mixture appear cloudy or milky.

Is this normal? Yes, this behavior is quite normal when you mix a solute that is soluble in one solvent (like Butylene Glycol) but has limited solubility in another (like water) into a combined system where the poor solvent (water) is present in a high concentration. The cloudiness indicates that the Activated Resorcinol is no longer fully dissolved in the final mixture.

Recommendations:

  • Reduce Concentration: Reduce the concentration of Activated Resorcinol in your final formulation.
  • Adjust Solvent Ratio: Increase the proportion of Butylene Glycol or other suitable solvents (like Ethanol or Propylene Glycol) relative to the water phase.
  • Consider Other Solvents: Research other effective solvents for Activated Resorcinol that are miscible with water.
  • Accept Cloudiness: Depending on the product type, a slightly cloudy appearance might be acceptable.

ผลิตภัณฑ์ที่เกี่ยวข้องที่กล่าวถึง

Butylene Glycol
Butylene Glycol
เครื่องสำอาง
Activated Resorcinol™ (4-Butyl Resorcinol)
Activated Resorcinol™ (4-Butyl Resorcinol)
เครื่องสำอาง