Solubility of Perfect-A 99% in Pentylene Glycol

Asked by: koolsaph On: October 30, 2023 Product Type: Cosmetics

Question

Can 0.2% Perfect-A 99% (Hydroxypinacolone Retinoate) be dissolved in Pentylene Glycol, and what percentage of Pentylene Glycol is required for complete dissolution in a formulation?

Answer

Dissolving Perfect-A 99% in Pentylene Glycol

Based on the information available, Perfect-A 99™ (Hydroxypinacolone Retinoate 99%) is soluble in glycols, and Pentylene Glycol is a type of glycol. Therefore, you should be able to dissolve Perfect-A 99™ at a concentration of 0.2% in a formulation containing Pentylene Glycol.

The product description for Perfect-A 99™ suggests mixing it in glycol (such as Ethoxydiglycol or Dimethyl Isosorbide) to help it dissolve well. While it confirms solubility in glycols, the exact minimum percentage of Pentylene Glycol required for complete dissolution of 0.2% Perfect-A 99™ is not specifically provided in the product information.

To ensure complete dissolution, it is recommended to use a sufficient amount of Pentylene Glycol. You may need to perform a small test to determine the minimum percentage required for your specific formulation, but using a reasonable amount of Pentylene Glycol in your formula should allow for the dissolution of 0.2% Perfect-A 99™.