Solubility of Pure-Apigenin™ and Phytosphingosine in LipidSoft™ Dry II

Based on the technical specifications of these ingredients, here is the solubility breakdown for LipidSoft™ Dry II (Dicaprylyl Carbonate):

1. Pure-Apigenin™ (Apigenin > 98%)

• Solubility: No, it cannot fully dissolve in LipidSoft™ Dry II.
• Details: Pure-Apigenin™ is generally insoluble in water and has very limited solubility in most oils. According to its specifications, it is soluble in organic solvents like ethanol and various glycols (such as Propanediol or Ethoxydiglycol).
• Recommendation: To incorporate Pure-Apigenin™ into a formula, it is recommended to use an emulsifier or dissolve it in a glycol first. It is best suited for cream or lotion formulations where it can be stabilized by the emulsification system.

2. Phytosphingosine (90% Purity)

• Solubility: Yes, it can dissolve in LipidSoft™ Dry II.
• Details: Phytosphingosine is a lipid-based ingredient. It can be mixed in the oil phase (such as LipidSoft™ Dry II) and requires heat (up to 80°C for about 15 minutes) to dissolve completely.
• Recommendation: Heat the LipidSoft™ Dry II to approximately 70-80°C, add the Phytosphingosine, and stir until clear before combining with the rest of your formula.

Summary

While Phytosphingosine will dissolve in LipidSoft™ Dry II with the help of heat, Pure-Apigenin™ will likely remain as a powder or precipitate because it requires a different type of solvent (glycols) or an emulsification system to be properly integrated.