Solubility of Quaternium-73 (Pure Powder) in Oil and Glycol for Cosmetics

Asked by: wimonrat.petpon On: December 02, 2025 Product Type: Cosmetics

Question

I am planning to use Quaternium-73 (Pure Powder) in a cosmetic formulation.

  • Which type of oil is recommended for dissolving Quaternium-73 (Pure Powder)?
  • Can Quaternium-73 (Pure Powder) be dissolved in glycol (such as Propylene Glycol or Butylene Glycol)?

Answer

Based on the product description for Quaternium-73 (Pure Powder) (ID 7370):

  1. Solubility in Oil: Yes, Quaternium-73 can be dissolved directly in oil. The product description explicitly states that it "Can dissolve in oil" and should be mixed by dissolving it directly in oil, while avoiding heat.
  2. Solubility in Glycol: The product description does not explicitly mention solubility in glycols (such as Propylene Glycol or Butylene Glycol). Since the product is confirmed to be oil-soluble, it is generally recommended to use the specified solvent (oil) for dissolution. If you wish to use a glycol, it is highly recommended to perform a small-scale test to confirm its solubility and stability in your specific glycol before proceeding with the full formulation.

Important Note: When mixing, remember to avoid high heat. Quaternium-73 can withstand high heat (up to 85°C) and a wide pH range (2-12), but the mixing instructions recommend avoiding heat during the dissolution process. The final product must also be protected from light (e.g., packaged in an opaque bottle) as the substance has a limitation on light stability.

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