Stronger Cooling Agents for Muscle Pain Relief Cream

Asked by: nattinee On: June 21, 2025 Product Type: Cosmetics

Question

I am developing a new muscle pain relief cream. I have tried using Freezeme and Cooltouch.

Could you please suggest other cooling agents that provide a stronger cooling sensation than these two?

Answer

Cooling Agents for Muscle Pain Relief Cream

Based on the cooling agents available, WS-10 Cooling Agent (Menthoxypropanediol) is described as providing a cooling sensation approximately 4.5 times stronger than menthol and is noted as having the highest cooling efficiency among the WS types listed (WS-10 > WS-5 > WS-3 > WS-12 > WS-23). This would likely be stronger than the products you have tried.

Other cooling agents suitable for skin include:

  • WS-23 Cooling Agent (Methyl Diisopropyl Propionamide): Provides a cooling sensation on the skin.
  • CoCool™ (Menthol+Menthyl Lactate): Provides a cooling sensation on the skin.
  • Water-Cool™ (Water-Soluble Cooling Agent): Provides a cool feeling on the skin and is water-soluble.

Note that Lip Cool™ (WS-3 Cooling Agent) is specifically for lip products and is not suitable for cooling the skin.

Follow-up Replies

nattinee
June 22, 2025 10:31
Question:

WS-10 Cooling Agent (Menthoxypropanediol) เป็น Synthetic หรือ natural derived คะ

Answer:

WS-10 Cooling Agent (Menthoxypropanediol): Synthetic or Natural?

WS-10 Cooling Agent (Menthoxypropanediol) is a synthetic cooling agent. Its chemical name, Menthoxypropanediol, indicates that it is a chemically synthesized compound, although it is derived from menthol, which is found naturally.