Sunscreen Formulation: Compatibility of Titanium Dioxide and Avobenzone

Based on the information reviewed, the ingredient Avobenzone (Butyl Methoxydibenzoylmethane) should not be used directly with Titanium Dioxide in sunscreen formulations, as it can cause Avobenzone to degrade quickly when exposed to UV light. This will result in a reduction of Avobenzone's effectiveness in protecting against UVA rays.

Therefore, if you prepare a sunscreen product containing Transparent Titanium Dioxide together with Avobenzone without using appropriate stabilizing technologies or agents, it is highly likely that the effectiveness of Avobenzone will be reduced.