Super-HYA™ vs. Small Molecule Hyaluronic Acid: Size, Absorption, and Penetration

Asked by: misix24 On: April 28, 2021 Product Type: Cosmetics

Question

Regarding Super-HYA™ (Sodium Acetylated Hyaluronate, AcHA), which is highlighted for its better skin absorption, I'm curious about its molecular size in Daltons. Is the size smaller than Hyaluronic Acid (Small Molecule) found in Double Hyaluron Liquid? Can it penetrate deeper into the skin than Hyaluronic Acid (Small Molecule)? Or is its size larger and penetration shallower, but it has better absorption?

Answer

Super-HYA™ vs. Small Molecule Hyaluronic Acid

Based on the product descriptions, here is a comparison between Super-HYA™ (Sodium Acetylated Hyaluronate, AcHA) and the Small Molecule Hyaluronic Acid found in Double Hyaluron Liquid:

  • Molecular Size: The Small Molecule Hyaluronic Acid (Nano size) in Double Hyaluron Liquid has an average molecular weight of approximately 10,000 Daltons. The description for Super-HYA™ does not specify its exact molecular weight in Daltons.

  • Absorption and Penetration:

    • The Small Molecule Hyaluronic Acid (Nano size) at 10,000 Daltons is described as being able to be absorbed into the skin to provide deep moisture.
    • Super-HYA™ (Sodium Acetylated Hyaluronate) is a modified form of hyaluronic acid. Its structure has been partially replaced with an acetyl group, giving it both oil-loving (lipophilic) and water-loving (hydrophilic) characteristics. This unique structure allows it to absorb into the skin much better than standard hyaluronic acid types. The description states it has the "maximum absorption into the skin" compared to other types of Hyaluronate.

In summary, while the Small Molecule Hyaluronic Acid (Nano size) in Double Hyaluron Liquid (approx. 10,000 Daltons) can penetrate the skin for deep hydration, Super-HYA™ is specifically designed for enhanced absorption due to its modified chemical structure, allowing it to interact more effectively with the skin's layers.

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