Whitening Serum Formulation and MSH White Solubility

Question

I have a whitening serum formulation with the following ingredients and percentages:

Activated Resorcinol 1%
MSH White 2%
Tranexamic Acid 3%
Gluco Bright 4%
Niacinamide 5%
Dimethyl Isosorbide 3%
Natural Bisabolol 1%
Light Cream Maker 1%
Xanthan Gum 0.5%
Tocopheryl Acetate 0.5%
Allantoin 0.5%
Disodium EDTA 0.2%
Mild Preserved Eco 1%
Water (remaining percentage)

Regarding the formula above, can MSH White be mixed directly? Or should I use a substance to help dissolve it first, as the product information states it dissolves in oil with heat?

If I use Squalane 5% to dissolve MSH White with heat, can I then mix it into the formula?

MySkinRecipes Expert · Accepted Answer

Whitening Serum Formulation

Regarding your whitening serum formulation and the question about dissolving MSH White:

Based on the product information, MSH White (Undecylenoyl phenylalanine) needs to be dissolved in the oil phase using heat (at least 60°C, recommended 80°C) before incorporating it into the rest of the formula.

Your proposed method of dissolving MSH White in Squalane with heat is correct and appropriate for incorporating MSH White into your serum formulation. Squalane is an oil that can act as the oil phase for dissolving MSH White using heat as required by the MSH White product instructions.

Your formula includes several effective whitening and skin-benefiting ingredients such as Activated Resorcinol, Tranexamic Acid, Gluco Bright, and Niacinamide, along with supporting ingredients like Dimethyl Isosorbide for penetration, Natural Bisabolol for soothing, Vitamin E and Allantoin for skin conditioning, and Disodium EDTA and Mild Preserved Eco for stability and preservation. Light Cream Maker and Xanthan Gum are used for emulsification and thickening.

Ensure all ingredients are mixed according to their specific instructions for optimal results and stability.