A natural substance found in fish and human nerve tissue. can reduce wrinkles, lift skin, anti-oxidant It also helps to enhance the effectiveness of other antioxidants. Provides good performance at an affordable price

DMAE (Dimethylaminoethanol), the active ingredient of all Dr.Perricone anti-aging products ( Perricone MD) is a natural substance. stimulates the synthesis Phosphatidylcholine It is found in most fish and human nerve tissues. can reduce wrinkles, tighten skin, anti-oxidant It also helps to enhance the efficacy of other antioxidants.

DMAE (SkinTight MD™) Liquid Processed to reduce the smell of the ingredients The deodorization of DMAE, which has a strong odor and adjusts the pH, can be readily added to any formulation.

Using DMAE in Anti-Wrinkle Formulas Usually results can be seen after about 10 days of continuous use. Suitable for use with other anti-aging peptides. to help enhance efficiency and make the results faster and clearer

DMAE is suitable for use with Vitamin B5 It will increase efficiency when used together.

Precautions for using DMAE Maiden

Although DMAE is highly effective in reducing the appearance of wrinkles, face lifting But there is a disadvantage Not suitable for use with sensitive skin because DMAE can irritate the skin. when used in high concentrations Therefore, to reduce the risk of allergic reactions and skin irritations. It should not be used at the highest levels recommended by the manufacturer. for beginners should be used at a level not more than half In addition, the addition of anti-irritant ingredients to formulations containing DMAE can reduce irritation caused by DMAE. Maiden

Use: Can be used in all forms of anti-aging cosmetic formulations.

Mixing method: mix in the final step The temperature of the cosmetics must be below 40. °C Maiden

Usage rate: 1-10% (recommended 3%, use above 5% may irritate the skin. and make it very gooey)

Product characteristics: Clear liquid with a characteristic odor

Solubility: can dissolve in water

Storage: Store at room temperature do not expose to heat For long term storage Can be stored in a cool place, temperature 6-8 degrees, shelf life 2 years.

INCI Name : DIMETHYLAMINOETHANOL TARTRATE (50% concentration as Bitartrate form) Maiden

Toner DMAE Recipe Example

distilled water, the rest

DMAE (SkinTight MD™) Liquid 5-10%

Preservative 0.5%

research results

Research article: Skin Res Technol. 2002 Aug;8(3):164-7. Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel. Uhoda I, Faska N, Robert C, Cauwenbergh G, Piérard GE. . Unit of Dermocosmetology, Department of Dermatopathology, University Medical Center of Liège, CHU Sart Tilman, B-4000 Liège, Belgium. Maiden

Conclusion: DMAE is effective in increasing skin firmness.

Research article: Am J Clin Dermatol. 2005;6(1):39-47. The role of dimethylaminoethanol in cosmetic dermatology. Grossman R. Johnson and Johnson Consumer Products Worldwide, Skillman, NJ 08558, USA. Maiden

Conclusion: A 3% concentration of DMAE Gel for 16 weeks can reduce forehead wrinkles and eye marks.

Research Article: Br J Dermatol. 2007 Mar;156(3):433-9. The antiwrinkle effect of topical concentrated 2-dimethylaminoethanol involves a vacuolar cytopathology. Morissette G, Germain L, Marceau F. Center de Recherche en Rhumatologie et Immunologie, Center Hospitalier Universitaire de Quebec, Quebec QC, Canada.

Conclusion: The use of DMAE at a concentration of 3% resulted in thickening of the skin (epidermis) and reduction of wrinkles.

Research article: Phytomedicine. 2007 Nov;14(11):711-5. Randomized, placebo-controlled, double-blind, split-face study on the clinical efficacy of Tricutan on skin firmness. Sommerfeld B. Dermatology Clinic, Danavägen 7B, SE-18131 Lidingö, Sweden. bea.hudmontt@telia.com Maiden

Conclusion: In a trial involving 25 women, DMAE was able to help lift and tighten the skin. and increase the elasticity (elasticity) of the skin

Maiden

Research article: Pharmazie. 2009 Dec;64(12):818-22. In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation. Tadini KA, Campos PM. Department of Pharmaceutical Sciences, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, University of São Paulo, Brazil. ktadini@fcfrp.usp.br Maiden

Conclusion: DMAE can increase collagen thickness. Thickening of the epidermis and increased skin hydration (hydrating) after 8 weeks of continuous use.

Examples of products that use DMAE as their main ingredient

Perricone MD's anti-aging product line uses DMAE as the main ingredient in every item.