Acceptability of DMSO as a Solvent for Research (Despite Cosmetic Warning)

Asked by: Anonymous On: October 09, 2025 Product Type: Food

Question

I am planning to use Dimethyl Sulfoxide (DMSO, 99.9%) (Product ID 6854) as a solvent in my research work to dissolve turmeric extract powder.

However, the product description includes a strict warning: "Do not use in cosmetics."

Is it acceptable to use DMSO for dissolving the extract powder in a laboratory research setting, or does this violate the usage restrictions?

Answer

The use of DMSO (Dimethyl Sulfoxide) to dissolve turmeric extract powder for research work is generally acceptable and a common practice in laboratory settings.

The warning "Do not use in cosmetics" is a crucial regulatory and safety disclaimer. This warning applies specifically to the use of DMSO in finished commercial cosmetic products that are intended to be applied to the skin.

Why the warning exists:
DMSO is a powerful penetration enhancer. Its use in commercial cosmetics is often restricted or prohibited by regulatory bodies (like the EU) because it can increase the absorption of other ingredients, potentially including harmful or unapproved substances, deep into the skin.

Conclusion for your research:

  • If your research is purely for solubility testing, analysis, or academic study, using DMSO as a solvent for your turmeric extract is fine.
  • However, if your research is aimed at developing a final product for sale as a cosmetic, the final formulation must not contain DMSO to comply with most cosmetic regulations.

The product you are referring to is:

  • ID 6854: Dimethyl sulfoxide (DMSO, 99.9%)

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