Adding GreyReverse™ to Commercial Hair Products: Stability, Compatibility, and Preservation Concerns

It is generally not recommended to add active ingredients like GreyReverse™ (Palmitoyl Tetrapeptide-20) to existing commercial hair care products. This practice can lead to several problems related to stability, compatibility, and efficacy, as commercial products are carefully formulated and balanced.

Here are the key concerns and precautions you should be aware of:

1. Stability and Heat Sensitivity

GreyReverse™ is a peptide that is sensitive to heat and should not be exposed to heat during mixing. While adding it to a finished product is usually done at room temperature, the overall stability of the peptide in the final, unoptimized mixture is a major concern.

2. Compatibility (Solubility)

GreyReverse™ is water-soluble (dissolves in water/glycerin base).

• It will only mix properly with water-based products (like hair tonics, sprays, or light serums).
• It will not disperse or be effective if added to oil-based products, thick creams, or conditioners with high oil content.

3. Preservation Risk

Commercial products have a carefully balanced preservative system. Adding a water-based ingredient like GreyReverse™ can dilute the existing preservatives, potentially leading to microbial contamination and spoilage of the entire product.

4. Efficacy and Concentration

The recommended usage rate for GreyReverse™ is 1-5% (5% is recommended for a head spray) to be effective in reducing gray hair. Adding a small amount to a large bottle of an existing product will likely dilute the active ingredient below the effective concentration, making the addition pointless.

5. pH Compatibility

Peptides often require a specific pH range (typically slightly acidic to neutral, around pH 4.0-7.0) to remain stable and effective. The pH of the commercial product you are adding it to might be outside this range, causing the peptide to degrade.

Recommendation

For the best results and stability, it is strongly recommended to use GreyReverse™ in a newly formulated product, such as a simple hair tonic or spray, at the recommended 5% concentration. This ensures proper stability, preservation, and optimal efficacy.