Adding Ingredients to Your Serum Formulation

Yes, it is possible to add the ingredients you listed to a serum formulation, but you need to consider the properties and mixing requirements of each ingredient.

Here is a breakdown for each ingredient:

• Centella Asiatica Extract (Madecassoside 90%): This is a powder that is water-soluble up to 1%. It should be added in the final step of the formulation, without heat, and the final pH should be between 4 and 6.5. It helps stimulate collagen, reduce wrinkles, and calm skin.
• Orange Peel Extract: This is a water-soluble powder. It should be added in the final step, when the temperature is below 40°C, and the pH is between 3.5 and 7.0. It can help with dark circles and has anti-glycation effects. Note that it might cause a warming sensation.
• Aloe Vera Extract (extraction ratio 10:1 FullAssay™): This is a water-soluble liquid. It should be mixed into the water phase. It is an electrolyte and might affect the viscosity of your serum, potentially making it thinner. The pH should be between 3.5 and 7.
• Kojic Acid Dipalmitate: This is an oil-soluble powder that requires heating (60-80°C) to dissolve. It must be mixed into the oil phase of your formulation. The final formula pH should be between 3 and 9. It is effective for skin whitening.

Considerations for your formula:

1. Compatibility: Ensure your base serum formula can accommodate both water-soluble and oil-soluble ingredients if you plan to add Kojic Acid Dipalmitate. If your serum is purely water-based, adding Kojic Acid Dipalmitate will be challenging as it needs an oil phase to dissolve properly with heat.
2. Mixing Method: You will need to adjust your mixing process to incorporate ingredients at the correct temperature and phase (water vs. oil).
3. pH Adjustment: The optimal pH range for these ingredients varies slightly, but a final pH between 4 and 6.5 would generally be suitable for most of them, keeping in mind the specific requirements for each.
4. Viscosity: Adding Aloe Vera Extract might reduce the viscosity of your serum.
5. Usage Rates: Refer to the recommended usage rates for each ingredient (typically 0.1-2% for Centella Asiatica Extract, 1-5% for Orange Peel Extract, 1-10% for Aloe Vera Extract, and 1-5% for Kojic Acid Dipalmitate) and consider the total percentage of added ingredients to ensure the formula remains stable and effective.

By carefully considering the properties and mixing instructions for each ingredient, you can successfully incorporate them into your serum formulation.