Adding Niacinamide and Glucosamine to Existing Lotion

Based on the previous replies:

Yes, you can dissolve Vitamin B3 (Niacinamide) and Glucosamine (N-acetyl-D) in water first, as they are water-soluble.

• If your existing lotion contains water, you can likely mix the dissolved solution directly into the lotion.
• If your lotion does not contain water, you should dissolve the ingredients in a small amount of water first, and then carefully mix this solution into the lotion.

Regarding your other questions:

• Compatibility: Yes, you absolutely need to consider the ingredients in your existing lotion. Some ingredients might not be compatible with Niacinamide or Glucosamine, which could affect the stability, texture, or efficacy of the final product. As suggested by the staff, posting the ingredient list of your lotion would help determine potential compatibility issues.
• Percentages: Yes, percentages are very important. The percentages you mentioned (5% B3, 4% Glucosamine) are the concentrations of the pure ingredients. When you add these dissolved ingredients to your lotion, the final percentage of B3 and Glucosamine in the total mixture will be lower than 5% and 4%, respectively, depending on the amount of lotion you use. You need to calculate the final percentages based on the total weight/volume of the mixture. Also, ensure that the final concentration of these ingredients in the lotion does not exceed recommended usage limits for safety and efficacy. Adding too much can potentially cause irritation or instability.

In summary, while it's possible to add these ingredients, you must consider the compatibility with your existing lotion's ingredients and accurately calculate the final percentages in the total mixture to ensure safety and effectiveness.