Using Vitamin B3 and Glucosamine with Lotion

Yes, you can mix Vitamin B3 (Niacinamide) and Glucosamine (N-acetyl-D) purchased from the store directly into a lotion or cream base. These ingredients are water-soluble powders and are designed to be incorporated into cosmetic formulations like lotions, serums, or creams.

There is no complex process required before mixing, other than ensuring they are properly dissolved in the water phase of your formulation if you are making a product from scratch. When adding to an existing lotion, you would typically dissolve the powder in a small amount of water first before mixing it thoroughly into the lotion.

Regarding using them together, Vitamin B3 (Niacinamide) and Glucosamine (N-acetyl-D) can be used together and are often combined in formulations. Research indicates that using N-acetyl Glucosamine together with Niacinamide can be particularly effective for benefits such as reducing hyperpigmentation (dark spots) and improving skin tone. They work synergistically.

Mixing and Usage:

• Both ingredients should be mixed into the water phase of a formulation.
• The optimal pH range for formulations containing these ingredients is generally between 3-8, with a range of 4.0-7.0 often recommended for Niacinamide and 3-7 for Acetyl Glucosamine.
• Recommended usage rates vary, but typically Niacinamide is used at 1-10% (with high-purity types like Safe-B3™ or Extreme-B3™ allowing up to 10% without significant flushing), and Acetyl Glucosamine (like GlucoBright™) is used at 1-8% (often recommended at 4% when combined with Niacinamide at 2-4%).

Important Consideration:
As mentioned in the reply you received, it is crucial to calculate the correct amount of powder to add to your lotion base to achieve the desired final percentage in your product. The method provided in the reply is a correct way to calculate this amount based on the weight of your lotion.

Always ensure the ingredients are fully dissolved and mixed evenly into your lotion base for best results.