Adjusting pH of Stabilized Vitamin C Serum for Stability and FDA Compliance
คำถาม
How can I adjust the pH of Stabilized Vitamin C (Natural-C Glycol™) Serum to meet FDA requirements (pH 3.0 or higher) while maintaining its stability? The staff mentioned adding a weak base like Triethanolamine and using a pH meter, but also warned against exceeding pH 3.0 due to Vitamin C degradation. What is the recommended procedure and the reasoning behind the pH limit?
คำตอบ
Adjusting pH of Stabilized Vitamin C (Natural-C Glycol™) Serum for Stability and FDA Compliance
Based on the information provided, the Stabilized Vitamin C (Natural-C Glycol™) Serum is formulated for stability and is generally recommended for use as a finished product. However, to meet current FDA regulations which require cosmetic products to have a pH of at least 3.0 (please verify the latest regulations), you can adjust the pH upwards.
To adjust the pH while minimizing impact on stability:
- Gradually add a weak base, such as Triethanolamine 99%, in small amounts.
- Mix thoroughly after each addition.
- Use a pH meter to accurately measure the pH level.
- Adjust the pH until it reaches 3.0.
Important Considerations:
- The staff recommendation and product information indicate that increasing the pH above 3.0 will accelerate the degradation of the Vitamin C, compromising its stability and effectiveness. Therefore, it is crucial not to exceed a pH of 3.0 when adjusting.
- Always confirm the latest FDA regulations regarding cosmetic pH requirements, as these can change.
Following these steps allows you to meet the minimum pH requirement for FDA registration while maintaining the best possible stability for the Stabilized Vitamin C (Natural-C Glycol™) Serum.
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Triethanolamine 99%
