Alternatives to Oil for Dissolving Oil-Soluble Vitamins E and A

Vitamin E (dl-alpha tocopherol) and Vitamin A Palmitate (retinyl palmitate/retinol palmitate) are oil-soluble ingredients. While traditional oils or oil-based emollients like LipidSoft™ Lite are effective solvents, you are looking for non-oil alternatives to use in a formula containing PE-1Aqua and Pentylene Glycol for enhanced skin penetration.

Here's an evaluation of the alternatives you mentioned:

• Ethoxydiglycol: This is a versatile solvent and carrier that is soluble in water, glycols, and natural oils. It can help dissolve various substances and enhance their penetration into the skin. It is a potential option for dissolving or incorporating these oil-soluble vitamins in a non-oily system.

• Isododecane: This is an ultra-lightweight emollient and solvent that is suitable for oil-free formulations. It can dissolve oil-soluble substances and evaporates quickly, leaving a non-greasy feel. This is another viable alternative to traditional oils.

• Flora Solve™ Clear: This ingredient is designed to solubilize oils and fragrances into water-based systems, creating clear microemulsions. It is effective at dissolving oils and can help incorporate oil-soluble vitamins into a non-oily or water-based formula.

• Pentylene Glycol: While Pentylene Glycol is a useful solvent and humectant, it is primarily water-soluble. It is less likely to effectively dissolve oil-soluble vitamins like Vitamin E (dl-alpha tocopherol) and Vitamin A Palmitate compared to the other options you mentioned or traditional oils.

In summary, Ethoxydiglycol, Isododecane, and Flora Solve™ Clear are potential non-oil alternatives that can help dissolve or incorporate oil-soluble Vitamin E (dl-alpha tocopherol) and Vitamin A Palmitate into your formulation, aligning with your goal to avoid traditional oils while utilizing penetration enhancers like PE-1Aqua and Pentylene Glycol. Pentylene Glycol itself is less suitable for dissolving these oil-soluble vitamins directly. It is recommended to perform testing to determine the optimal concentration and method for incorporating these vitamins using the chosen alternative solvent in your specific formula.