Anti-Wrinkle Essence/Serum Formulation

Here is a suggested formulation for an anti-wrinkle essence or serum based on your requested ingredients:

• Distilled water: 50%
• Repair Activator™ (Bifida Ferment Lysate): 10%
• Pep®-Coll (Palmitoyl Tripeptide-5): 3%
• Pal-GHK, Pal-GQPR (Matrixyl 3000): 5%
• Acetyl Hexapeptide-8 (Argireline): 10%
• Beta Glucan (Saccharomyces cerevisiae extract): 5%
• Adenosine Liposome: 3%
• Methylsilanol Mannuronate: 6%
• Rhamnose: 3%
• Phospholipid: 1%
• 1,2-Hexanediol: 3%
• Mild Preserved Eco™: 1%

Notes on Formulation:

• Many of the active ingredients, such as the peptides (Pep®-Coll, Matrixyl 3000, Acetyl Hexapeptide-8) and Repair Activator™, should be added in the final cooling phase of the formulation, typically below 40°C, to maintain their efficacy.
• The optimal pH range for many of these ingredients is between 3.5 and 6.5, with some being stable up to pH 9. Aiming for a final pH in the range of 5-6 would likely be suitable for most components.
• Beta Glucan disperses in water and may require a slightly viscous formula to prevent settling.
• You specified Adenosine Liposome. The search found Pure-Adenosine™ powder. Phospholipid can help with the dispersion of ingredients and potentially aid in creating a liposomal structure or enhancing penetration.
• Ensure all ingredients are fully dispersed or dissolved according to their specifications. Some ingredients like Phospholipid require thorough blending.
• Proper storage conditions, such as refrigeration for some ingredients (Repair Activator™, Pep®-Coll, Matrixyl 3000, Acetyl Hexapeptide-8, Beta Glucan, Pure-Adenosine™, Phospholipid), are important for long-term stability.