Applying Vitamin C and B3 Serums Separately: Timing and Layering

Asked by: sittatta_ On: November 11, 2023 Product Type: Cosmetics

Question

If Vitamin C and B3 (Niacinamide) serums should not be mixed in the same bottle, what is the recommended waiting time when applying them separately from different bottles for optimal efficacy, or should they not be layered at all?

Answer

Subject: Regarding applying Vitamin C and Vitamin B3 (Niacinamide) separately.

You are correct that it is generally advised not to mix Vitamin C (especially L-Ascorbic Acid) and Vitamin B3 (Niacinamide) in the same bottle due to potential interactions, although modern formulations often minimize this risk.

Regarding your questions:

  1. If applying from separate bottles, how long should you wait between applications for best efficacy?

    • It is recommended to apply them separately. If using a Vitamin C serum with a low pH (like L-Ascorbic Acid), apply it first. Wait about 5-15 minutes for it to absorb and for the skin's pH to return to normal before applying the Vitamin B3 serum. This waiting period helps ensure each ingredient works optimally and minimizes the chance of interaction or irritation.
  2. Or, should you not apply them layered at all?

    • It is generally acceptable to layer them with a waiting period as mentioned above. Alternatively, you can use one serum in your morning routine and the other in your evening routine. This is also a great way to incorporate both ingredients without any concern about layering or waiting times, and it can be particularly beneficial for sensitive skin.

In summary, applying them separately with a short waiting time is a good approach, or using them at different times of the day is also an effective strategy.