Bakuchiol and Formulation Compatibility

1. Bakuchiol and Clogged Pores

Yes, Bakuchiol can help address issues related to clogged pores, similar to how retinoids work. Bakuchiol has been shown to:

• Reduce sebum production
• Control hyperkeratinization
• Help control acne breakouts, especially when used alongside ingredients like Salicylic Acid.

These mechanisms contribute to clearer pores, similar to the effects seen with retinoids like Retinol and Retinal.

2. Formula Compatibility

Let's review the compatibility of your proposed formula:

• Isododecane 20%
• Squalane 76%
• Bakuchiol 1%
• Dimethyl Isosorbide 3%

The total percentage is 100%. This is an oil-based formulation.

Isododecane and Squalane Solubility

Isododecane is a hydrocarbon and is soluble in other hydrocarbons like Squalane. Therefore, Isododecane and Squalane will mix well together in your formula.

Overall Formula Compatibility

• Bakuchiol is oil-soluble and will dissolve effectively in the Isododecane and Squalane base.
• Dimethyl Isosorbide (DMI) is a carrier often used to enhance the penetration of active ingredients, including Bakuchiol. While its primary solubility is in water, glycols, and some specific oils like mineral oil and silicone oil, it is commonly used in oil-based systems containing oil-soluble actives like Bakuchiol to improve their delivery. At 3%, DMI is expected to be compatible with your Isododecane and Squalane blend and help carry the Bakuchiol.

Based on the properties of the ingredients, your proposed formula appears compatible.