Combining High and Low Molecular Weight Gamma-Polyglutamic Acid

Yes, you can use different molecular weights of Gamma-Polyglutamic Acid, such as High Molecule Weight and Low Molecule Weight, together in a formulation. Combining different molecular weights can provide multi-level hydration benefits to the skin.

• High Molecular Weight: Tends to form a film on the skin surface, providing immediate hydration and reducing transepidermal water loss.
• Low Molecular Weight: Can penetrate deeper into the skin layers, offering hydration and potentially other benefits below the surface.

By using both, you can achieve more comprehensive moisturization.

Regarding the amount, the recommended usage rate for Gamma-Polyglutamic Acid products is generally 0.1% to 1%, with 0.3% to 0.5% being commonly recommended for optimal results. When combining different molecular weights, the total concentration of all types of Gamma-Polyglutamic Acid in your formulation should stay within this recommended range.

For example, if you aim for a total concentration of 0.5% in your formula, you could use:

• 0.25% Gamma-Polyglutamic acid (High Molecule Weight)
• 0.25% Gamma-Polyglutamic acid (Low Molecule Weight)

Or you could adjust the ratio based on the specific feel and performance you desire, as long as the combined total is within the recommended usage rate for the final product.