Combining Liquid Azelaic™ and AcnePLEX™

Yes, Liquid Azelaic™ and AcnePLEX™ can potentially be used together in a cosmetic formulation, but careful consideration is needed due to the active nature of both ingredients.

• Liquid Azelaic™ (Potassium azeloyl diglycinate) is effective for brightening skin, reducing dark spots, controlling oiliness, and reducing acne. It is a water-soluble and generally gentler form of Azelaic Acid.
• AcnePLEX™ is an acne treatment technology that works by restoring the skin barrier and killing P. Acnes bacteria. It contains ingredients like ceramides, phytosphingosine, Royal Jelly extract, and Salicylic Acid.

Combining multiple active ingredients, especially those targeting acne and oiliness, can increase the risk of skin irritation. Therefore, when formulating with both:

• Consider Compatibility: AcnePLEX™ has a positive charge and requires the use of non-ionic thickeners (like HEC or HPMC) if you are creating a gel or cream formulation. Ensure all ingredients in your formula are compatible.
• Adjust Concentrations: Start with lower recommended usage rates for each ingredient to minimize potential irritation.
• Check pH: Ensure the final pH of your formulation is suitable for both ingredients and skin tolerance. Liquid Azelaic™ is recommended for pH 5-11.

It is always recommended to test the final formulation on a small area of skin first to check for any adverse reactions.